BRCA Mutation Frequency and Penetrance: New Data, Old Debate
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چکیده
منابع مشابه
BRCA mutation frequency and penetrance: new data, old debate.
EDITORIALS 1675 More than a decade after the discovery of the BRCA1 and BRCA2 genes, a consensus has yet to emerge regarding the frequency and precise magnitude and spectrum of cancer risks for individuals carrying mutations of these genes. Although these questions constitute a topic of heated debate among cancer epidemiologists ( 1 – 9 ) , they are also of clinical concern to women and men con...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2006
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/djj500